Devout Catholics have followed a tradition that goes back thousands of years. They obtained a circular strand of beads/gemstone beads called Rosario. The beads are used by individuals to count off prayers, and decades while the rosary was recited.
Most people have an affinity to certain colors, certain materials that reflect their inner faith, strength, and conviction and should start their search with that in mind. You can find padre pio rosary from https://catholically.com/collections/padre-pio-relic-rosary.
Start with your church, most but not all do rosary sell and maybe just what you are looking for. In some smaller communities, you may have trouble finding a vendor to a rosary/rock your needs.
If you know what you want as far as material, gemstone, style, etc. You can contact a designer of the custom rosary in your area or one of the online vendors. Be aware that anything can be adjusted quite a bit more expensive than the design of an assembly line is more or less standard.
More high-end custom rosary made with a precious metal link that is used to attach beads one to the other. The most common metals used are silver, but gold and platinum can be used. Bead material can vary from plastic, glass, or precious gemstones.
Most Catholics see the cross as an important part of their rosaries. Designs can vary from very simple to elaborate. And materials can range from exotic polished hardwoods, for precious and semi-precious metals.